Conjugated complement cascade inhibitors

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/48 (2006.01) A61P 5/00 (2006.01) A61P 7/00 (2006.01) A61P 9/10 (2006.01) A61P 17/00 (2006.01) A61P 17/02 (2006.01) A61P 19/02 (2006.01) A61P 21/04 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) A61P 37/06 (2006.01) A61P 41/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2530480

The present invention is directed to conjugated complement cascade inhibitors, and a method of treating a patient using a conjugated complement cascade inhibitor. The present invention is directed, in part, to compounds comprising a conjugated complement cascade inhibitor. The compounds may advantageously bind to a receptor in a component of the complement cascade, and may thereby inhibit the complement cascade or inhibit the effects of the proteins which are formed from the cascade (for example C3a and C5a). In one embodiment, the present invention provides a pharmaceutical for treating a patient, comprising a conjugated complement inhibitor. In another embodiment, the present invention provides a method of treating a patient to suppress activation of the complement cascade, comprising administering a conjugated complement inhibitor to the patient. These and other aspects of the invention will become more apparent from the present description and claims.

Cette invention concerne des inhibiteurs de la cascade de compléments conjugués, et sur un procédé de traitement d'un patient au moyen d'un inhibiteur de la cascade de compléments conjugués.

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