C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 7/18 (2006.01) C07C 33/02 (2006.01) C07C 43/14 (2006.01) C07C 43/15 (2006.01) C07C 43/178 (2006.01) C07C 45/29 (2006.01) C07C 45/51 (2006.01) C07C 47/24 (2006.01) C07C 47/263 (2006.01) C07C 47/277 (2006.01) C07C 49/24 (2006.01) C07C 49/255 (2006.01) C07C 49/587 (2006.01) C07C 69/007 (2006.01) C07C 69/025 (2006.01) C07C 69/732 (2006.01) C07D 303/14 (2006.01) C07D 309/12 (2006.01)
Patent
CA 2045079
ABSTRACT The present invention is directed to conjugated diene compounds of the general formula: Image (I) wherein R1 is Image (in which R3 and R4 are independently an alkyl group of 1 to 4 carbon atoms or taken together form a cyclic alkyl group), Image (in which R5 is an allcyl group of 1 to 4 carbon atoms) or Image (in which X is a hydroxy group, a halogen atom or -OSO2R6 (R6 is an alkyl group of 1 to 4 carbon atoms optionally substituted by a halogen atom or a phenyl group optionally substituted by 1 to 4 carbon atoms)), and R2 is a hydrogen atom, Image (in which R7 is a hydrogen atom or an alkyl group of 1 to 4 carbon atoms, R8 is an alkyl group of 1 to 4 carbon atoms, or R7 and R8 taken together may form a ring), Image (in which R9 - R11 are independently an alkyl group of 1 to 4 carbon atoms or a phenyl group) or an acyl group, with the proviso that when R1 is Image and X is a substituent other than a hydroxy group, R2 is not a hydrogen atom which are industrially advantageous intermediates for preparing sarcophytol A. Sarcophytol A as an anticarcinogenenic promotor or antitumor agent.
Kitano Yasunori
Morinaka Yasuhiro
Takayanagi Hisao
Kirby Eades Gale Baker
Mitsubishi Chemical Corporation
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