C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/04 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2505090
The present invention provides modified oligomeric compounds that modulate gene expression via an RNA interference pathway. The oligomeric compounds of the invention include one or more conjugate moieties that can modify or enhance the pharmacokinetic and pharmacodynamic properties of the attached oligomeric compound.
L'invention concerne des composés oligomères modifiés qui modulent l'expression génique via une voie d'interférence de l'ARN. Ces composés oligomères comprennent une ou plusieurs fractions conjuguées qui peuvent modifier ou renforcer les propriétés pharmacocinétiques et pharmacodynamiques du composé oligomère fixé.
Baker Brenda
Bhat Balkrishen
Crooke Stanley T.
Eldrup Ann B.
Griffey Richard H.
Baker Brenda
Bhat Balkrishen
Crooke Stanley T.
Eldrup Ann B.
Griffey Richard H.
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