Conjugates

C - Chemistry – Metallurgy – 07 – K

Patent

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167/129, 530/7.1

C07K 14/02 (2006.01) A61K 39/00 (2006.01) C07K 17/02 (2006.01)

Patent

CA 2009896

ABSTRACT Hepatitis R core antigen (HBcAg) particles, which carry a polypeptide which presents an antigenic epitope and which are suitable for use in vaccines, are composed of HBcAg provided with a N-terminal extension incorporating a Lys residue and the said polypeptide is coupled to the particles via the side chain amino group of the Lys residue.

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