Conjugates as therapies for cancer and prostate diseases

Details Conjugates as therapies for cancer and prostate diseases Conjugates as therapies for cancer and prostate diseases

A - Human Necessities

61

K

A61K 47/48 (2006.01) C07C 45/46 (2006.01) C07C 67/343 (2006.01) C07D 207/34 (2006.01) C07D 219/10 (2006.01) C07D 235/18 (2006.01) C07D 295/185 (2006.01) C07D 307/79 (2006.01) C07D 307/92 (2006.01) C07D 311/92 (2006.01) C07D 317/70 (2006.01) C07D 487/22 (2006.01) C07D 493/04 (2006.01) C07K 5/103 (2006.01) C07K 7/06 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2368801

Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as prostate-specific antigen (PSA) and cathepsin B are provided, as well as compositions comprising these conjugates. Methods of using these conjugates in the treatment of prostate diseases are also provided.

L'invention concerne des conjugués peptidiques dans lesquels des agents cytocides et cytostatiques, tels que des analogues de polyamine et des naphtoquinones, sont conjugués avec un polypeptide reconnu et clivés par des enzymes, telles que l'antigène spécifique de la protaste et la cathépsine B, ainsi que des compositions comprenant lesdits conjugués. Des méthodes d'utilisation desdits conjugués dans le traitement de maladies de la prostate sont également décrites.

Affiliated with

Also associated with

Rating

Conjugates as therapies for cancer and prostate diseases does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Conjugates as therapies for cancer and prostate diseases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Conjugates as therapies for cancer and prostate diseases will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1746764