Conjugates containing hydrophilic spacer linkers

Details Conjugates containing hydrophilic spacer linkers Conjugates containing hydrophilic spacer linkers

C - Chemistry, Metallurgy

07

K

C07K 9/00 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) C07H 17/02 (2006.01) C07K 5/06 (2006.01) C07K 5/078 (2006.01) C07K 5/093 (2006.01) C07K 5/10 (2006.01) C07K 5/11 (2006.01) C07K 7/06 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2690943

Described herein are compositions and methods for use in targeted drug delivery using cell- surface receptor binding drug delivery conjugates containing hydrophilic spacer linkers for use in treating disease states caused by pathogenic cell populations.

L'invention concerne des compositions et des procédés destinés à être utilisés dans la délivrance ciblée de médicaments en utilisant des conjugués de délivrance de médicaments liant un récepteur de surface cellulaire contenant des lieurs espaceurs hydrophiles destinés à être utilisés dans le traitement d'états pathologiques provoqués par des populations de cellules pathogènes.

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