Conjugates for medical imaging comprising carrier, targeting...

Details Conjugates for medical imaging comprising carrier, targeting... Conjugates for medical imaging comprising carrier, targeting...

A - Human Necessities

61

K

A61K 51/08 (2006.01) A61K 49/08 (2006.01)

Patent

CA 2516409

This invention relates to the delivery of agents to the body. One particular class of such agents are contrast agents useful in medical imaging techniques. The agents may be metals useful as contrast agents in magnetic resonance imaging (MRI), or in nuclear imaging, including positron emission tomography (PET), or as therapeutic agents in radiotherapy. The agents may alternatively be contrast agents useful in X-ray imaging. The invention also relates to methods by which agents for delivery to the body can be coupled to carriers and to targeting moieties effective to direct the agent to a specific locus within the body.

L'invention concerne l'administration d'agents dans un corps. Une classe particulière de tels agents sont des agents de contraste utiles dans des techniques d'imagerie médicale. Les agents peuvent être des métaux utiles comme agents de contraste dans l'imagerie par résonance magnétique (IRM) ou dans l'imagerie nucléaire, notamment la tomographie par émission de positrons (PET) ou comme agents thérapeutiques dans la radiothérapie. Les agents peuvent, de manière alternative, être des agents de contraste utiles dans l'imagerie par rayons x. L'invention concerne également des procédés permettant de coupler des agents à administrer dans le corps à des véhicules et des fractions de ciblage efficaces pour diriger l'agent dans un locus spécifique dans le corps.

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