Conjugates for the administration of biologically active...

Details Conjugates for the administration of biologically active... Conjugates for the administration of biologically active...

C - Chemistry, Metallurgy

07

K

C07K 19/00 (2006.01) A61K 39/39 (2006.01) A61K 47/48 (2006.01) C07K 14/775 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2727811

The invention relates to a conjugate that comprises an Apo A molecule or a functionally equivalent variant thereof and a compound of therapeutic interest wherein both components are covalently coupled as well as to the use of said conjugates in therapy for the specific targeting of said compounds to those tissues showing specific binding sites for the ApoA molecule.

La invención se relaciona con un conjugado que comprende una molécula de Apo A o una variante funcionalmente equivalente de la misma y un compuesto de interés terapéutico en donde ambos componentes se encuentran unidos covalentemente así como a los usos de dichos conjugados en terapia para el direccionamiento específico de dichos compuestos a aquellos tejidos que presentas sitios de unión específicos para la molécula de ApoA.

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