A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/39 (2006.01) A61K 39/02 (2006.01) A61K 39/095 (2006.01) A61K 47/48 (2006.01) C07K 14/205 (2006.01) C07K 14/35 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2131551
A conjugate compound comprises at least one heat shock protein or portion thereof including at least one immunostimula- tory domain and at least one capsular oligosaccharide or polysaccharide of a pathogenic bacteria. The compound comprises oli- gosaccharides of the Meningococci C (MenC) group and a heat shock protein selected from M. bovis BCG GroEl-type 65kDa hsp (hspR65); recombinant M. tuberculosis DnaK-type 70kDa hsp (hspR70) and a heat shock protein from H. pylori. The conju- gate compounds are useful in the preparation of vaccines to prevent bacterial infection.
Costantino Paolo
Norelli Francesco
Rappuoli Rino
Viti Stefano
Biocine S.p.a.
Borden Ladner Gervais Llp
Novartis Vaccines And Diagnostics S.r.l.
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