A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01)
Patent
CA 2723821
Conjugates of a cholinesterase moiety and one or more nonpeptidic, water soluble polymers are provided. Typically, the nonpeptidic, water soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided, among other things, are compositions comprising conjugates, methods of making conjugates, and methods of administering compositions to a patient.
La présente invention concerne des conjugués d'un groupe fonctionnel cholinestérase et d'un ou plusieurs polymères non peptidiques solubles dans l'eau. Typiquement, le polymère non peptidique soluble dans l'eau est le polyéthylène glycol ou un dérivé de ce composé. L'invention concerne également, entre autres, des compositions comprenant les conjugués, des procédés de fabrication des conjugués et des procédés d'administration des compositions à un patient.
Bossard Mary J.
Fernando Lal A. R.
Lee Seoju
Zappe Harold
Gowling Lafleur Henderson Llp
Nektar Therapeutics
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