Conjugates of a gm-csf moiety and a polymer

A - Human Necessities – 61 – K

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A61K 47/48 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2573262

Conjugates of a GM-CSF moiety and one or more water-soluble polymers are provided. Typically, the water-soluble polymer is poly(ethylene glycol) or a derivative thereof. Also provided are compositions comprising conjugates, methods of making conjugates, and methods of administering compositions comprising conjugates to a patient.

L'invention concerne des conjugués de fraction GM-CSF et un ou plusieurs polymère(s) soluble(s) dans d'eau. Le polymère soluble dans d'eau est généralement un poly(éthylène glycol) ou un dérivé de celui-ci. L'invention concerne également des compositions renfermant lesdits conjugués, des procédés de production de ces conjugués et des méthodes d'administration des compositions renfermant les conjugués à un patient.

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