Conjugates of anti-rg-1 antibodies

A - Human Necessities – 61 – K

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A61K 47/48 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2707443

Anti-RG-1 antibodies, antibody fragments, or antibody mimetics conjugated to partner molecules, such as drugs, radioisotopes, and cytotoxins, wherein the partner molecule exerts its effect regardless of whether the RG-1 bound conjugate is internalized within a targeted cell, are useful for treating cancers.

La présente invention concerne des anticorps anti-RG-1, des fragments d'anticorps, ou des mimétiques d'anticorps conjugués à des molécules partenaires, telles que des médicaments, des radio-isotopes, et des cytotoxines, la molécule partenaire exerçant son effet que le conjugué lié à RG-1 soit internalisé au sein d'une cellule cible ou non, qui sont utiles dans le traitement des cancers.

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