Conjugates of antibody and duoarmycin derivatives as...

Details Conjugates of antibody and duoarmycin derivatives as... Conjugates of antibody and duoarmycin derivatives as...

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61P 35/00 (2006.01) C07D 403/06 (2006.01) C07D 403/14 (2006.01) C07D 487/10 (2006.01)

Patent

CA 2569679

Methods for treating a neoplastic disease with an antibody-cytotoxin conjugate molecule, methods of synthesizing an antibody-cytotoxin conjugate molecule are provided. Compounds that are useful as antibody-cytotoxin conjugate molecule or useful in the synthesis of these molecules are also provided.

L'invention concerne des méthodes de traitement d'une maladie néoplasique avec une molécule de conjugué anticorps-cytotoxine, ainsi que des méthodes de synthèse d'une molécule de conjugué anticorps-cytotoxine. Elle porte également sur des composés utiles en tant que molécule de conjugué anticorps-cytotoxine ou utiles dans la synthèse de ces molécules.

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