Conjugates of anticoagulant and protein

Details Conjugates of anticoagulant and protein Conjugates of anticoagulant and protein

C - Chemistry, Metallurgy

08

B

167/104, 530/15.

C08B 37/10 (2006.01) A61L 33/00 (2006.01) C08H 1/00 (2006.01)

Patent

CA 1214459

CONJUGATES OF ANTICOAGULANT AND PROTEIN Abstract of the Disclosure Conjugates are provided which are covalently bonded conjugates of an anticoagulant and protein that are prepared in the presence of a coupling agent that forms amide linkages between the anticoagulant and the protein. Such amide linking coupling agents exclude highly toxic coupling agents such as CNBr. These conjugates are useful for enhancing the blood compatibility of certain surfaces of a prosthetic device, a surgical apparatus, or an extra-corporeal medical device.

417634

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