Conjugates of insulin-like growth factor binding protein-4...

A - Human Necessities – 61 – K

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A61K 47/48 (2006.01)

Patent

CA 2498062

A conjugate consisting of insulin-like growth factor binding protein 4 (IGFBP- 4) and one or two poly(ethylene glycol) group(s), said poly(ethylene glycol) group(s) having an overall molecular weight of from about 30 to about 40 kDa is disclosed. This conjugate is useful for the treatment of cancer.

L'invention concerne un conjugué comprenant une protéine de liaison du facteur de croissance insulinomimétique 4 (IGFBP-4) et un ou deux groupes poly(éthylène glycol) possédant un poids moléculaire global compris entre environ 30 et environ 40 kDa. Ce conjugué est utile pour le traitement du cancer.

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