Conjugates of poorly immunogenic antigens and synthetic...

Details Conjugates of poorly immunogenic antigens and synthetic... Conjugates of poorly immunogenic antigens and synthetic...

A - Human Necessities

61

K

A61K 39/385 (2006.01) A61K 39/015 (2006.01) A61K 39/02 (2006.01) A61K 39/112 (2006.01) A61K 39/21 (2006.01) A61K 39/39 (2006.01) C07K 14/16 (2006.01) C07K 14/445 (2006.01) C07K 14/47 (2006.01) C07K 17/02 (2006.01) C07K 19/00 (2006.01)

Patent

CA 2141454

The invention relates to conjugates of poorly immunogenic antigens, e.g. peptides proteins and polysaccharides, with a synthetic peptide carrier constituting a T cell epitope derived from the sequence of human heat shock protein hsp65, or an analog thereof, said peptide or analog being capable of increasing substantially the immunogenicity of the poorly immunogenic antigen. Suitable peptides according to the invention are Pep278h, which corresponds to positions 458-474 of human hsp65, and Pep II, which corresponds to positions 437-448 of human hsp65, but in which two cysteine residues at positions 442 and 447 are replaced serine residues.

Affiliated with

Also associated with

Rating

Conjugates of poorly immunogenic antigens and synthetic... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Conjugates of poorly immunogenic antigens and synthetic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Conjugates of poorly immunogenic antigens and synthetic... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1522714