Conjugates of soluble peptidic compounds with...

Details Conjugates of soluble peptidic compounds with... Conjugates of soluble peptidic compounds with...

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/49 (2006.01) A61K 47/48 (2006.01) C07C 323/41 (2006.01) C07C 323/59 (2006.01) C07K 14/315 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01) C12N 9/64 (2006.01) C12N 9/72 (2006.01) C12N 15/12 (2006.01) C12N 15/58 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2260288

Soluble derivatives of soluble polypeptides incorporating membrane binding elements, their use in therapy and methods and intermediates including peptide membrane binding elements. Preferred membrane-binding elements are fatty acid derivatives or polylysine-containing sequences.

L'invention concerne des dérivés solubles de polypeptides solubles renfermant des éléments de liaison de membranes, ainsi que leur utilisation en thérapie, des procédés et des intermédiaires comprenant des éléments de liaison de membranes de peptides. Les éléments de liaison de membranes préférés sont des dérivés d'acides gras ou des séquences contenant de la polylysine.

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