Conjugates or co-administration of igf-1 receptor ligands...

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/48 (2006.01) A61K 38/28 (2006.01) A61K 38/30 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2542834

The present invention provides a method of treating cancer involving administering an insulin-like growth factor-1 receptor (IGF-1 receptor) agonist and an anti-cancer chemotherapeutic agent. Also provided are compounds for treating cancer comprising an IGF-1-receptor ligand coupled to an anti- cancer chemotherapeutic agent. Also provided are compounds for treating cancer comprising an insulin-receptor ligand coupled to an anti-cancer chemotherapeutic agent.

L'invention concerne une méthode qui permet de traiter le cancer et qui consiste à administrer un agoniste du récepteur de facteur de croissance insulinoïde-1 (récepteur de IGF-1) et un agent chimiothérapeutique anticancéreux. L'invention concerne également des composés qui permettent de traiter le cancer et qui contiennent un ligand du récepteur de IGF-1 couplé à un agent chimiothérapeutique anticancéreux. L'invention concerne en outre des composés qui permettent de traiter le cancer et qui contiennent un ligand du récepteur de l'insuline couplé à un agent chimiothérapeutique anticancéreux.

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