Conjunctival tissue system

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/071 (2010.01) A61B 17/00 (2006.01) A61K 35/12 (2006.01) A61L 27/60 (2006.01) C12N 5/02 (2006.01)

Patent

CA 2642947

The present disclosure describes a tissue system with conjunctival cells, including conjunctival stem cells. The conjunctival tissue system is derived from isolated tissue comprising conjunctival cells, and is suitable for restoring ocular surface impairments, particularly those that result from damaged or diseased conjunctiva. The tissue system is generated using a simple single medium culture scheme, and a support material, such as human amniotic membrane. The conjunctival tissue system generate is suitable for transplantation to treat the ocular surface of an eye of a subject that is damaged or diseased.

La présente invention concerne un système de tissu à cellules conjonctives, y compris des cellules souches conjonctives. Le système de tissu conjonctif est dérivé de tissu isolé qui comprend des cellules conjonctives, et convient pour réparer des troubles de la surface oculaire, en particulier des troubles qui résultent d'une conjonctive endommagée ou malade. Le système de tissu est produit au moyen d'un simple plan de culture en milieu unique et d'un matériau de support, tel qu'une membrane amniotique humaine.Le système de tissu conjonctif produit convient pour une transplantation pour traiter la surface oculaire d'un AEil endommagé ou malade d'un sujet.

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