Connective tissue growth factor-2

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/18 (2006.01) A61K 38/18 (2006.01) C07K 14/475 (2006.01) C07K 16/22 (2006.01)

Patent

CA 2194765

The present invention relates to a human CTGF-2 polypeptide and DNA (RNA) encoding such polypeptide. Also provided is a procedure for producing such polypeptide by recombinant techniques and antibodies and antagonist/inhibitors against such polypeptide. Also provided are methods of using the polypeptide therapeutically for enhancing the repair of connective and support tissue, promoting the attachment, fixation and stabilization of tissue implants and enhancing wound healing.

La présente invention concerne le facteur-2 de croissance des tissus conjonctifs, lequel est un polypeptide, et l'ADN (ARN) codant ce polypeptide. L'invention concerne également un procédé pour produire un tel polypeptide par des techniques de recombinaison et des anticorps, des antagonistes et des inhibiteurs contre ledit polypeptide. L'invention concerne également les méthodes d'utilisation thérapeutiques du polypeptide pour favoriser la réparation des tissus conjonctifs et de soutien, favoriser la fixation, l'immobilisation et la stabilisation d'implants de tissus et accélérer la cicatrisation des lésions.

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