C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/40 (2006.01) A61K 39/12 (2006.01) A61P 31/14 (2006.01) C07K 14/18 (2006.01)
Patent
CA 2720166
Consensus CHIKV E1 protein, consensus CHIKV E2 protein, consensus CHIKV capsid protein, or fragments and homologues thereof, and nucleic acid molecules that encode the same are disclosed. A consensus CHIKV Env protein which in-cludes CHIKV E1 consensus protein, CHIKV E2 consensus protein, CHIKV E3 consensus protein, or fragments and homologues thereof and nucleic acid molecules that encode the same are also disclosed. Compositions and recombinant vaccines comprising CHIKV consensus proteins, and methods of using them are disclosed.
La présente invention concerne la protéine consensus CHIKV E1, la protéine consensus CHIKV E2, la protéine de capside consensus CHIKV, ou leurs fragments et homologues, et les molécules dacide nucléique qui codent pour celles-ci. La présente invention concerne également la protéine consensus CHIKV Env qui comprend la protéine consensus CHIKV E1, la protéine consensus CHIKV E2, la protéine consensus CHIKV E3, ou leurs fragments et homologues et les molécules dacide nucléique qui codent pour celles-ci. La présente invention concerne en outre des compositions et des vaccins recombinants comprenant les protéines consensus CHIKV, et des procédés pour leur utilisation.
Muthumani Karuppiah
Weiner David B.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
The Trustees Of The University Of Pennsylvania
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