Conserved hbv and hcv sequences useful for gene silencing

Details Conserved hbv and hcv sequences useful for gene silencing Conserved hbv and hcv sequences useful for gene silencing

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 31/7088 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2528510

Conserved consensus sequences from known hepatitis B virus strains and known hepatitis C virus strains, which are useful in inhibiting the expression of the viruses in mammalian cells, are provided. These sequences are useful to silence the genes of HBV and HCV, thereby providing therapeutic utility against HBV and HCV viral infection in humans.

L'invention porte sur des séquences de consensus conservées de souches connues de virus de l'hépatite B et de l'hépatite C, utiles pour inhiber chez l'homme l'expression desdits virus. Ces séquences utiles pour effectuer le silençage des gènes du VHB et du VHC présentent de ce fait une utilité thérapeutique contre les infections par le VHB et le VHC de l'homme.

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