Construction of west nile virus and dengue virus chimeras...

A - Human Necessities – 61 – K

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A61K 39/12 (2006.01) A61K 39/295 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2472468

The present invention relates to attenuated, immunogenic West Nile virus chimeras built on a dengue virus backbone for the production of immunogenic, live, attenuated West Nile virus vaccines.

La présente invention concerne des chimères de virus du Nil occidental immunogènes et atténuées, construites à partir du squelette du virus de la dengue. Ces chimères permettent de produire des vaccins contre le virus du Nil occidental atténués, vivants et immunogènes..

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