Contact lens and eye drop rewetter compositions and their uses

Details Contact lens and eye drop rewetter compositions and their uses Contact lens and eye drop rewetter compositions and their uses

A - Human Necessities

61

K

A61K 31/728 (2006.01) A61K 9/08 (2006.01) A61K 31/047 (2006.01) A61K 31/717 (2006.01) A61K 31/765 (2006.01) A61K 47/02 (2006.01) A61K 47/04 (2006.01) A61P 27/04 (2006.01)

Patent

CA 2512320

Stable ophthalmic formulations comprising hyaluronic acid (sodium hyaluronate) as the primary active demulcent ingredient, stabilized oxy-chloro complex (available commercially as OcuPure(tm) from Advanced Medical Optics, Purite® from Allergan, and Purogene from Biocide) for preservative efficacy, balanced salts mimicking the tear film, and sodium borate as a buffer are disclosed. In one embodiment, preferred stable formulations may be used in the human eye with or without contact lenses. In another embodiment preferred formulations may also be used as a storage and conditioning solution for contact lenses following disinfection.

L'invention concerne des préparations ophtalmiques stables contenant de l'acide hyaluronique (hyaluronate de sodium) en tant qu'ingrédient émollient actif primaire, un complexe oxychloro stabilisé (disponible commercialement sous forme d'OcuPure(tm) d'Advanced Medical Optics, de Purite® d'Allergan, et de purogène de biocide) qui engendre une efficacité de préservation, des sels équilibrés imitant le film lacrymal, et du borate de sodium comme tampon. Dans un mode de réalisation, des préparations stables préférées peuvent être utilisées dans l'oeil humain avec ou sans lentilles de contact. Dans un mode de réalisation, des préparations préférées peuvent également être utilisées comme une solution de conditionnement et de stockage pour lentilles de contact, suite à une désinfection.

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