Container closure delivery system

Details Container closure delivery system Container closure delivery system

B - Operations, Transporting

67

D

B67D 7/78 (2010.01) B65D 83/76 (2006.01)

Patent

CA 2593748

A container closure delivery system that is suitable for lyophilized pharmaceutical injectable powder products is disclosed. The system comprises storage stable powder formulations and a container closure assembly design wherein the formulation can be filled and lyophilized with a standard fill finish equipment, and the formulations and lyophilization processes are optimized to produce a powder that readily dissolves upon contact with a diluent, thereby facilitating the direct injection of the lyophilized product without the need for a separate reconstitution/mixing/priming step.

La présente invention a trait à un système de distribution de fermetures d'emballages approprié pour des produits pulvérulents injectables pharmaceutiques lyophilisés. Le système comporte des formulations pulvérulentes stables au stockage et un modèle d'ensemble de fermeture de récipient dans lequel la formulation peut être remplie et lyophilisée à l'aide d'un équipement de finition de remplissage standard, et les processus de formulations et de lyophilisation sont optimisés pour produire une poudre qui se dissout facilement lors d'un contact avec un diluent, facilitant ainsi l'injection directe du produit lyophilisé sans nécessiter une étape distincte de reconstitution/mélange/amorçage.

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