Continuous centrifugation system and method for directly...

B - Operations – Transporting – 01 – D

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B01D 45/12 (2006.01) A61M 1/30 (2006.01) B04B 5/04 (2006.01) A61M 1/26 (2006.01) A61M 1/36 (2006.01)

Patent

CA 1321986

Abstract of the Disclosure A system for continuously separating lighter and intermediate density matter, such as plasma rich in plate- lets from whole blood moves blood through a diverging cen- trifugation gap (65) between inner and outer walls of a rotor (42) rotating about a central axis within an outer housing. The centrifugation action creates layered flow along an intermediate section. However by crating trail- ing wakes in the gap between the rotor (42) and housing (11), localized remixing patterns tending to move in the opposite direction are induced in the layered matter. Platelet rich plasma may then be extracted through adjacent platelet concentrate ports (58) on the inner wall of the rotor (42). An interior passageway system passes the platelet rich plasma to a platelet concentrate reservoir (23). Recirculation of blood in the rotor- housing gap between the output and input, and pumping action provided by the diverging centrifugation gap (65), aid in enhancing throughput and concentration levels. Prior to the centrifugation gap (65) an initial narrow gap section is employed to limit backward propagation of the induced circulatory patterns.

556330

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