G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/00 (2006.01)
Patent
CA 2595725
The present invention relates to methods and apparatuses for cell separation. In particular, the invention relates to separation of a particular cell type from a mixture of different cell types based on the differential rolling property of the particular cell type on a substrate coated with molecules that exhibits adhesive property with the particular cell type. This technology is adaptable for use in implantable shunts and devices for cell trafficking or tumor neutralization.
Cette invention concerne des méthodes et des dispositifs de séparation cellulaire. Plus particulièrement, cette invention concerne la séparation d'un type de cellule particulier d'un mélange constitué de différents types de cellules sur la base d'une propriété de roulement différente du type de cellule particulier sur un substrat enrobé de molécules présentant une propriété adhésive avec ce type de cellule particulier. Cette technologie peut être mise en oeuvre dans des dispositifs et des shunts implantables destinés au trafic cellulaire ou à la neutralisation d'une tumeur.
Charles Nichola
Clark Nathan
Gentile John P.
King Michael R.
Liesveld Jane
Ridout & Maybee Llp
University Of Rochester
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