Continuous intravenous infusion of adenosine to human patients

A - Human Necessities – 61 – K

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167/202

A61K 31/70 (2006.01) C07H 19/16 (2006.01) C07H 19/167 (2006.01)

Patent

CA 1301652

Abstract Adenosine is administered to human patients by continuous intravenous infusion at levels at which the heart blocking action of adenosine is not detected to modify the hemodynamic properties of the patient. Specific indications of use are induction of controlled hypotension, control of hypertensive crisis, effecting preferential coronary vasodilation, increasing blood flow in a coronary artery graft, increasing cardiac output, reducing platelet loss during coronary bypass surgery and facilitation of the induction of cardioplegia.

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