Continuous mammalian cell lines having monocyte-macrophage...

C - Chemistry – Metallurgy – 12 – P

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195/122.6, 195/3

C12P 21/00 (2006.01) C12N 5/00 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2002025

33 IP-0697 TITLE CONTINUOUS MAMMALIAN CELL LINES HAVING MONOCYTE/MACROPHAGE CHARACTERISTICS AND THEIR ESTABLISHMENT IN VITRO ABSTRACT Continuous mammalian cell lines having monocyte/macrophage characteristics which have been established from normal mammalian cells, continuous human cell lines having monocyte/macrophage characteristics which are substantially free of malignant cells, and a method for establishing such cell lines through long-term culturing of normal mammalian cells with periodic, partial medium changes during culturing are provided. -33-

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