Continuous method for preparing pharmaceutical granules

Details Continuous method for preparing pharmaceutical granules Continuous method for preparing pharmaceutical granules

A - Human Necessities

61

K

A61K 9/16 (2006.01)

Patent

CA 2399034

. The invention concerns a method for formulating in the form of granules one or several active pharmaceutical principles, characterised in that it consists in continuously introducing various ingredients to be granulated and in granulating said mixture using a device comprising a chamber and at least a rotary stirring arm, and in the presence of a sufficient amount of a binder solution until said granules are obtained.

La présente invention a pour objet un procédé pour formuler sous forme de granulés un ou plusieurs principes actifs pharmaceutiques, caractérisé en ce que l'on procède en mode continu à l'introduction des différents ingrédients à granuler et à la granulation de ce mélange au moyen d'un dispositif comprenant une enceinte et au moins un bras d'agitation rotatif, et en présence d'une quantité efficace d'une solution liante jusqu'à l'obtention desdits granulés.

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