Continuous process for the preparation of sucrose 6-esters

Details Continuous process for the preparation of sucrose 6-esters Continuous process for the preparation of sucrose 6-esters

C - Chemistry, Metallurgy

07

H

C07H 13/04 (2006.01) C07H 5/02 (2006.01) C07H 9/04 (2006.01)

Patent

CA 2069130

A method is provided for the preparation of a sucrose 6-ester by: (i) reacting sucrose with a trialkyl orthoester or with a ketene acetal in an inert organic solvent in the presence of an acid catalyst to provide a sucrose alkyl 4,6-orthoester, (ii) treating tho sucrose alkyl 4,6-orthoester under mild aqueous acidic conditions to provide a mixture of sucrose 4- and 6-monoesters, (iii) treating the mixture of esters with a base to convert the sucrose 4-ester into sucrose 6-ester, and (iv) neutralising the solution and isolating the sucrose 6-ester, an acidic ion exchange resin being used to catalyse preparation of the sucrose alkyl 4,6-orthoester and to effect its hydrolysis. Sucralose is prepared by chlorinating the sucrose 6-esters prepared.

Affiliated with

Also associated with

Rating

Continuous process for the preparation of sucrose 6-esters does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Continuous process for the preparation of sucrose 6-esters, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Continuous process for the preparation of sucrose 6-esters will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1888909