Contraceptive composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/785 (2006.01) A61P 15/18 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2640978

The present invention relates to a contraceptive composition including an effective amount of a dendrimer compound including one or more naphthyl disulphonic acid surface groups, or a pharmaceutically acceptable salt or solvate of the dendrimer compound; and a pharmaceutically acceptable carrier, excipient and/or diluent therefor. The contraceptive composition may also exhibit antimicrobial activity. The invention also relates to a method of selectively reducing or preventing conception in a female animal, including a human, which method includes administering to the animal an effective amount of a contraceptive composition which composition includes an effective amount of a dendrimer compound including one or more naphthyl disulphonic acid surface groups, or a pharmaceutically acceptable salt or solvate of the dendrimer compound; and a pharmaceutically acceptable carrier, excipient and/or diluent therefor.

La présente invention concerne une composition contraceptive incluant une quantité active d'un composé dendrimère contenant un ou plusieurs groupements surfaciques de type acide naphtyldisulfonique, ou un sel ou solvate de qualité pharmaceutique dudit composé dendrimère ; ainsi qu'un vecteur, excipient et/ou diluant de qualité pharmaceutique dudit composé. La composition contraceptive peut également présenter une activité antimicrobienne. La présente invention concerne également une méthode de réduction ou de prévention sélective de la conception chez un animal femelle, y compris l'humain, ladite méthode incluant l'administration à l'animal d'une quantité active d'une composition contraceptive, ladite composition incluant une quantité active d'un composé dendrimère comprenant un ou plusieurs groupements surfaciques de type acide naphtyldisulfonique, ou un sel ou solvate de qualité pharmaceutique dudit composé dendrimère ; ainsi qu'un vecteur, excipient et/ou diluant de qualité pharmaceutique dudit composé.

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