Contraceptive targets

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/63 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2483323

The present invention relates generally to ovary-specific genes (O1-180, O1- 184 and O1-236) and the proteins they encode. Also provided are methods for detecting cell proliferative or degenerative disorders in reproductive tissues. Yet further, the invention provides methods for scrounge of compounds that interact and/or modulate the expression or activity of the ovary-specific genes. These compounds are possible contraceptive agents and/or fertility agents.

Cette invention a trait, d'une manière générale à des gènes spécifiques de l'ovaire (O1-180, O1-184 et O1-236) ainsi qu'aux protéines qu'ils codent. Elle porte également sur des techniques de détection de processus prolifératifs ou dégénératifs des cellules de tissus liés à la reproduction. Elle concerne, de surcroît, des méthodes de criblage de composés interagissant avec l'expression ou l'activité de gènes spécifiques de l'ovaire et/ou les modulant. Ces composés sont des agents potentiels de contraception et/ou de fertilité.

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