Contraceptive vaccine

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 39/00 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2193206

The instant invention is drawn to a sperm surface protein in substantially pure form selected from a human PH30 beta chain protein and a mouse PH30 beta chain proteins. Such proteins are useful as contraceptive vaccines in humans and mice respectively, and for identifying small molecules that will disrupt sperm-egg interaction and fertilization.

L'invention concerne une protéine superficielle de sperme essentiellement pure sélectionnée à partir d'une protéine humaine à chaîne bêta PH30 et de protéines de souris à chaîne bêta PH30. Ces protéines sont utiles comme vaccins contraceptifs chez l'homme et la souris respectivement, et pour identifier les petites molécules susceptibles d'entraver l'interaction sperme-ovule et la fécondation.

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