C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 39/00 (2006.01) C07K 14/705 (2006.01)
Patent
CA 2193206
The instant invention is drawn to a sperm surface protein in substantially pure form selected from a human PH30 beta chain protein and a mouse PH30 beta chain proteins. Such proteins are useful as contraceptive vaccines in humans and mice respectively, and for identifying small molecules that will disrupt sperm-egg interaction and fertilization.
L'invention concerne une protéine superficielle de sperme essentiellement pure sélectionnée à partir d'une protéine humaine à chaîne bêta PH30 et de protéines de souris à chaîne bêta PH30. Ces protéines sont utiles comme vaccins contraceptifs chez l'homme et la souris respectivement, et pour identifier les petites molécules susceptibles d'entraver l'interaction sperme-ovule et la fécondation.
Alves Kenneth
Gupta Sunil K.
Hollis Gregory Franklin
Merck & Co. Inc.
Ogilvy Renault
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