Contrast agent preparation

Details Contrast agent preparation Contrast agent preparation

C - Chemistry, Metallurgy

07

C

C07C 227/18 (2006.01) A61K 49/00 (2006.01) C07C 227/16 (2006.01) C07C 229/76 (2006.01) C07F 5/00 (2006.01)

Patent

CA 2287245

In the metallation of complexing agents such as DTPA-BMA with a lanthanide using a lanthanide oxide such as the lanthanide source, oxalic acid is used as a reaction accelerator.

L'invention concerne un procédé de métallation d'agents de complexion tels que DTPA-BMA avec un lanthanide, dans lequel un oxyde de lanthanide constitue la source de lanthanide et caractérisé par l'utilisation d'acide oxalique comme accélérateur de la réaction.

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