A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 49/00 (2006.01) A61K 47/48 (2006.01) A61K 49/08 (2006.01) A61K 51/06 (2006.01) C08G 79/00 (2006.01)
Patent
CA 2188292
The invention provides a blood pool contrast agent having an overall molecular weight of at least 10KD comprising a macrostructure which has bound thereto a plurality of opsonization inhibiting moieties and carries chelated ionic paramagnetic or heavy metal moieties, the chelant groups for said chelated moieties being macrocyclic where said macrostructure is liposomal.
L'invention se rapporte à un agent de contraste du pool sanguin ayant une masse moléculaire globale d'au moins 10 KD et comprenant une macrostructure à laquelle est liée une pluralité de fractions inhibant l'opsonisation et qui supporte des fractions chélatées de métaux lourds ou paramagnétiques, ioniques, les groupes de chélation de ces fractions chelatées étant macrocycliques lorsque cette macrostructure est liposomique.
Campion Brian
Fellmann Jere Douglas
Garrity Martha
Margerum Larry
Varadarajan John
Fetherstonhaugh & Co.
Nycomed Salutar Inc.
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