Contrast medium for thrombus formation

Details Contrast medium for thrombus formation Contrast medium for thrombus formation

C - Chemistry, Metallurgy

07

D

C07D 211/34 (2006.01) A61K 49/00 (2006.01) A61K 51/04 (2006.01) C07C 251/24 (2006.01) C07C 317/50 (2006.01) C07D 211/60 (2006.01) C07D 295/18 (2006.01)

Patent

CA 2558064

It is intended to provide a contrast medium for thrombus formation capable of binding specifically to a thrombus, lowering background noise and thus improving the resolution in a contrast examination for thrombus formation; and a method of detecting a thrombus by using the same. A contrast medium for thrombus formation comprising, as the active substance, a substance obtained by labeling a compound capable of binding to GPIIb/IIIa which is selected from among compounds represented by the general formulae (I) to (IV) and physiologically acceptable salts thereof; and a method of detecting a thrombus by using the same.

L'intention est de fournir un produit de contraste pour la formation d'un thrombus capable de se lier de façon spécifique à un thrombus, d'abaisser le bruit de fond et ainsi d'améliorer la résolution dans un examen radiologique à l'aide d'un moyen de contraste recherchant la formation d'un thrombus ; et procédé de détection d'un thrombus en utilisant celui-ci. Produit de contraste pour la formation d'un thrombus comprenant, comme substance active, une substance obtenue par marquage d'un composé capable de se lier à la GPIIb/IIIa qui est choisi parmi les composés représentés par les formules générales (I) à (IV) et les sels physiologiquement acceptables de ceux-ci ; et procédé de détection d'un thrombus en utilisant celui-ci.

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