Control of aberrant expression vector accumulation during...

C - Chemistry – Metallurgy – 12 – P

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195/86

C12P 1/00 (2006.01) C07K 14/61 (2006.01) C12N 15/67 (2006.01) C12N 15/70 (2006.01)

Patent

CA 2019696

X-7429 ABSTRACT The present invention provides a method for preventing the accumulation of aberrant expression vectors during fermentation processes which rely on the expression of an expression vector coded gene for production of a polypeptide product of interest. Antibiotics are added at approximately the time at which product expression begins.

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