Control of enterohemorrhagic e. coli o157:h7 in cattle by...

C - Chemistry – Metallurgy – 12 – N

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C12N 1/20 (2006.01) A23K 1/16 (2006.01) A61K 35/74 (2006.01) A61P 31/04 (2006.01) C12Q 1/02 (2006.01) C12Q 1/18 (2006.01) C12Q 1/68 (2006.01) A61K 39/108 (2006.01)

Patent

CA 2296763

Dominant probiotic bacterial strains have been isolated. The isolated bacterial strains fed to a ruminant animal are able to prevent the establishment of the pathogen E. coli O157:h7 in the animal. The strains can be re-isolated from the gastrointestinal tract contents of inoculated animals at about 28 days post-inoculation. Animals previously infected by E. coli O157:h7 can be treated to reduce or eliminate the pathogen by administering any of the dominant probiotic bacteria of the invention.

L'invention porte sur des souches bactériennes probiotiques dominantes que l'on a isolées, que l'on a administrées à un ruminant et qui peuvent empêcher l'établissement du pathogène E. Coli O157:H7 chez cet animal. On peut isoler à nouveau ces souches à partir du contenu du tractus gastro-intestinal des animaux inoculés, environ 28 jours après inoculation. On peut également traiter des animaux préalablement infectés par E. Coli O157:H7 afin de diminuer la présence de ce pathogène ou d'éliminer celui-ci, en administrant l'une quelconque des bactéries probiotiques dominantes de l'invention.

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