Control of es cell self renewal and lineage specification,...

Details Control of es cell self renewal and lineage specification,... Control of es cell self renewal and lineage specification,...

C - Chemistry, Metallurgy

12

N

C12N 5/00 (2006.01) C12N 5/071 (2010.01) C12N 5/0735 (2010.01) C12N 15/87 (2006.01)

Patent

CA 2484701

Self renewal of pluripotent cells in culture is promoted using a combination of an activator of a signalling pathway downstream of a receptor of the TGF- .szlig. superfamily and an activator of a gp130 downstream signalling pathway.

L'invention permet de favoriser l'autorenouvellement de cellules multipotentes en culture, à l'aide d'une combinaison d'un activateur de passerelle de signalisation en aval d'un récepteur de la superfamille des TGF-.beta. et d'un activateur de passerelle de signalisation en aval de gp130.

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