Control of intracellular target molecule by ip3...

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/00 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 3/12 (2006.01) A61P 25/00 (2006.01) A61P 27/02 (2006.01) A61P 27/06 (2006.01) A61P 27/12 (2006.01) A61P 43/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12N 15/09 (2006.01) C12Q 1/02 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2647769

It is intended to provide a composition containing an IP3 receptor binding protein (IRBIT), a nucleic acid controlling the expression/translation of the IRBIT or an antibody against the IRBIT which aims at controlling at least one intracellular biological function selected from among: (1) synthesis of a protein; (2) metabolism of an inositol phospholipid; and (3)the intracellular pH value.

L'invention concerne une composition contenant une protéine de liaison au récepteur IP3 (IRBIT), un acide nucléique contrôlant l'expression/la translation de l'IRBIT ou d'un anticorps anti-IRBIT dans le but de réguler au moins une fonction biologique intracellulaire choisie parmi : (1) la synthèse d'une protéine; (2) le métabolisme d'un inositol phospholipide; et (3) le pH intracellulaire.

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