C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/20 (2006.01) A61K 39/10 (2006.01)
Patent
CA 2138178
Bordetella species, such as Bordetella pertussis, is grown under aerobic conditions in a liquid culture medium containing nutrients for such growth. Enhanced cell density and antigen production are achieved by continuously determining the pH of the culture medium and, in response to such determination, simultaneously feeding, as required, (a) an acid, usually a mineral acid, such as hydrochloric acid, phosphoric acid or sulfuric acid, in a concentration sufficient to maintain the pH of the culture medium within a predetermined range of values, usually about pH 6.8 to about pH 7.3, and (b) a nutrient medium containing organic carbon and organic nitrogen, usually a neutral salt of an amino acid, such as monosodium glutamate, an amino acid, such as glutamic acid, or a mixture thereof.
Herbert Andrew
Kole Manoj
Lutzen Niels
Connaught Laboratories Limited
Sim & Mcburney
LandOfFree
Control of ph during bordetella growth does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Control of ph during bordetella growth, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Control of ph during bordetella growth will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1731102