Control of product selectivity in the addition of hcn to...

C - Chemistry – Metallurgy – 07 – H

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C07H 7/02 (2006.01) C07B 61/00 (2006.01) C07C 253/00 (2006.01) C07C 255/16 (2006.01) C07H 1/00 (2006.01) C07H 3/00 (2006.01)

Patent

CA 1321785

CONTROL OF PRODUCT SELECTIVITY IN THE ADDITION OF HCN TO ARABINOSE ABSTRACT Hydrogen cyanide addition to a monosaccharide results in a mixture of product cyanohydrins whose ratio can be changed by conducting the hydrogen cyanide addition in the presence of an agent which forms a complex with the monosaccharide. It is preferred to add the elements of hydrogen cyanide to a preformed complex of the monosaccharide. The product selectivity appears to be dependent upon the concentration of the complexing agent up to about one molar proportion of the latter relative to the monosaccharide with the selectivity being invariant thereafter.

590173

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