C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/16 (2006.01) A61K 38/10 (2006.01) A61K 38/12 (2006.01) A61P 31/12 (2006.01) A61P 31/18 (2006.01) C07K 5/00 (2006.01) C07K 5/06 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/005 (2006.01)
Patent
CA 2710964
The present invention relates to a peptide having one or more stable, internally-constrained HBS .alpha.- helices, where the peptide mimics at least a portion of a class I C-peptide helix or at least a portion of a class I N-peptide helix of a viral (e.g., HIV-I ) coiled-coil assembly. Methods of inhibiting viral infectivity of a subject by administering these peptides are also disclosed.
La présente invention concerne un peptide qui présente une ou plusieurs hélices a HBS stables, contraintes de manière interne, le peptide imitant au moins une partie d'une hélice de peptide C de classe I ou au moins une partie d'une hélice de peptide N de classe I d'un ensemble superhélice virale (par exemple VIH-I). L'invention concerne également des procédés d'inhibition de l'infectivité virale d'un sujet par l'administration de ces peptides.
Arora Paramjit S.
Wang Deyun
Gowling Lafleur Henderson Llp
New York University
LandOfFree
Control of viral-host membrane fusion with hydrogen bond... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Control of viral-host membrane fusion with hydrogen bond..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Control of viral-host membrane fusion with hydrogen bond... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2027679