Control release drug coating for medical devices

A - Human Necessities – 61 – L

Patent

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Details

A61L 31/10 (2006.01) A61L 27/34 (2006.01) A61L 27/54 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2656516

A medical device having multiple layers of a drug-loaded coating. At least one of the layers is more hydrophilic than at least another one of the layers. Also provided is a method for controlling the drug release profile from a coated medical device using multiple layers of modified and/or unmodified copolymers and varying the ratio of modified to unmodified copolymers.

La présente invention concerne un dispositif médical comportant de multiples couches d'un enrobage chargé en médicaments. Au moins une des couches est plus hydrophile qu'au moins une autre des couches. L'invention concerne également un procédé pour contrôler le profil de libération du médicament à partir d'un dispositif médical enrobé par l'utilisation de multiples couches de copolymères modifiés et/ou non modifiés et par la variation du rapport des copolymères modifiés aux copolymères non modifiés.

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