Control sequences of the human corin gene

Details Control sequences of the human corin gene Control sequences of the human corin gene

C - Chemistry, Metallurgy

12

N

C12N 15/85 (2006.01) A61K 31/7088 (2006.01) A61K 35/12 (2006.01) A61K 48/00 (2006.01) A61P 9/04 (2006.01) C12N 9/64 (2006.01) C12N 15/12 (2006.01) C12P 19/34 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2487024

This invention provides a novel expression control region isolated form mammalian corin genes. This control region preferentially activates transcription in cardiac cells. Methods and compositions are provided to employ this control region for identification of agents capable of modulating corin expression and for treatment of cardiac diseases.

L'invention concerne une nouvelle région de commande d'expression isolée à partir de gènes de corine de mammifère. Cette région de commande active de préférence la transcription dans les cellules cardiaques. L'invention concerne également des procédés et des compositions permettant d'utiliser cette région de commande pour l'identification d'agents pouvant moduler l'expression de corine et pour le traitement de maladies cardiaques.

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