Controlled absorption naproxen formulation for once-daily...

A - Human Necessities – 61 – K

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167/262

A61K 31/19 (2006.01) A61K 9/20 (2006.01) A61K 9/24 (2006.01) A61K 9/50 (2006.01)

Patent

CA 2034096

A naproxen formulation for oral administration on a once-daily basis comprises a first portion of the naproxen formulated in a multi- particulate pellet form designed to release the drug at a rate sufficient to maintain therapeutically effective blood levels substantially over 24 hours when administered each day on a once-daily basis and, optionally, a second portion of the naproxen formulated so as to release the drug promptly following administration so as to obtain a relatively immediate therapeutic response.

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