Controlled antacid delivery form and method of treatment...

Details Controlled antacid delivery form and method of treatment... Controlled antacid delivery form and method of treatment...

A - Human Necessities

61

K

167/123

A61K 9/24 (2006.01) A61K 9/22 (2006.01)

Patent

CA 1111766

CONTROLLED ANTACID DELIVERY FORM AND METHOD OF TREATMENT THEREWITH Abstract of the Disclosure A controlled antacid delivery form having an acid neutralizing component in a matrix including a gel- forming, swelling agent and a water insoluble lipid material. These materials are mixed with the antacid component, together with a large amount of sweet excip- ient, and compressed at high pressure to provide an ant- acid lozenge which dissolves very slowly in the mouth. A method for controlled antacid delivery where- in the controlled antacid delivery form is slowly dis- solved in the mouth and neutralizes the stomach acid over a long period of time with surprising little antacid, while bathing the esophageal lining with antacid. When the con- trolled antacid delivery form includes a mixture of ant- acids having different reactivities towards acid, said method provides for substantially complete utilization of each component.

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