Controlled degradation of expandable polymers in gastric...

A - Human Necessities – 61 – L

Patent

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A61L 27/50 (2006.01) A61F 2/02 (2006.01) A61L 27/14 (2006.01) A61L 27/54 (2006.01) A61M 29/04 (2006.01)

Patent

CA 2586568

Orally administrable polymer-carrying units for expanding in a stomach of a mammal to fill a space in the stomach, the polymer-carrying units including : a carrier; a plurality of polymer molecules expandable in aqueous solutions, releasably coupled to the carrier ; and means for selectively decoupling the polymer molecules from the carrier so that the polymer molecules and carrier are released in the stomach, are provided.

L'invention concerne des unités supportant des polymères et pouvant être administrées par voie orale, aux fins d'expansion dans l'estomac d'un mammifère, de manière à remplir un espace dans l'estomac, lesdites unités comprenant: un excipient; une pluralité de molécules de polymères expansibles en solutions aqueuses, couplées de manière amovible à l'excipient; et des moyens permettant de découpler de manière sélective les molécules de polymères de l'excipient, de manière que lesdites molécules et l'excipient soient libérés dans l'estomac.

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