Controlled delivery system of antifungal and keratolytic...

A - Human Necessities – 61 – K

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A61K 31/4174 (2006.01) A61K 9/08 (2006.01) A61K 45/06 (2006.01) A61K 47/10 (2006.01) A61K 47/16 (2006.01) A61K 47/30 (2006.01) A61K 47/44 (2006.01) A61P 31/10 (2006.01)

Patent

CA 2341814

A topical sustained release delivery system for delivery of antifungal agents to the finger or toenails achieving high penetration through the nails by combining the antifungal agent with a keratolytic agent and a humectant. The pharmaceutical sustained release topical preparation is provided in a varnish or spray form for treating the nail and surrounding tissues, where the active ingredient is an antifungal agent, a keratolytic agent, or preferably a combination of an antifungal and a keratolytic agent. The composition may further comprise an antibacterial, an antiviral, an antipsoriatic agents, or combinations thereof.

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